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Clotrimazole - Oral

Patient Medicine Information
Why do I need this medicine?
Clotrimazole is used to treat oral thrush (a fungal infection in the mouth that may spread to the back of the throat).

This medicine may also be used to prevent oral thrush in individuals with a weakened immune system due to certain conditions, such as undergoing cancer treatment or steroid therapy, or those who have had a kidney transplant.
How do I take this medicine?
Take Clotrimazole exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Try to take it at the same time each day.

This medicine is available as a lozenge. Suck the lozenge until the taste becomes strong, then lodge the lozenge between the gums and cheek. When the taste fades, start sucking it again. Repeat until the lozenge completely dissolves (about 30 minutes). Do not swallow.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the severity of your infection.

Take Clotrimazole at regular intervals. Do not skip any doses. You must complete the entire course of this medicine. If you don't, the infection will not be properly controlled.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Do not take Clotrimazole if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to this medicine or any of its ingredients.
What should I take note of while taking this medicine?
Inform your doctor if you have liver disease.

Let your doctor know if you are pregnant or breastfeeding.

Be sure to check with your doctor or pharmacist before giving Clotrimazole to a child. Children may be more sensitive to the side effects.

Maintain good oral hygiene as this is important in managing fungal infections.

For as long as you are taking this medicine, you may need to have regular blood tests to check your liver function. Your doctor will advise you about how often you need to have blood tests.
What side effects could I experience?
Clotrimazole may cause any of the following side effects: nausea, vomiting, unpleasant sensations in the mouth, and itchy skin.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • yellowing of the skin or eyes, abdominal pain, dark coloured urine, tiredness, swelling in the legs and ankles
  • rashes, breathlessness, swelling of the face, eyes or mouth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor and pharmacist if you are taking or using medicines used in organ transplants or certain immune disorders such as tacrolimus and sirolimus.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Avoid freezing.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on Clotrimazole - Oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2026 MIMS. All rights reserved. Powered by MIMS.com
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