Anti-D immunoglobulin is used to prevent formation of antibodies during pregnancy when a mother has Rh-negative blood and the baby is Rh-positive. It may also be given after a person with Rh-negative blood receives a transfusion with Rh-positive blood.
Anti-D immunoglobulin injection is to be given intramuscularly (into the muscle), usually into the muscles of your upper arm or upper thigh.
Your doctor or nurse will administer the injection for you.
Do not use Anti-D immunoglobulin if you ever had an allergic reaction (rashes, breathlessness, swollen eyes) to human immunoglobulin products.
Alert your doctor if you have the following conditions:
- severe blood disorders
- immunoglobulin A deficiency
- Rh(D) positive
as Anti-D immunoglobulin may not be suitable for you.
Inform your doctor if you have bleeding disorders.
Let your doctor know if you are breastfeeding.
Inform your doctor if you have been recently vaccinated. Do not receive any vaccinations without first asking your doctor.
Your doctor may need to perform blood tests to check your response to this medicine.
Anti-D immunoglobulin may cause any of the following side effects: headache, dizziness, fever, chills, weakness, paleness, diarrhoea, nausea, vomiting, muscle or joint pain, rash, sweating and pain, redness, warmth and swelling at injection site.
If you develop rashes, breathlessness, swollen mouth or eyes, stop using Anti-D immunoglobulin and inform your doctor quickly. These could be signs of an allergic reaction.
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Do not use Anti-D immunoglobulin with live attenuated vaccines (e.g. measles, mumps, rubella or varicella) during treatment and within 3 months after treatment with Anti-D immunoglobulin.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Avoid alcohol.
Store in the refrigerator, between 2-8 °C. Do not allow to freeze. If frozen, anti-D immunoglobulin will become ineffective and should not be used.
Protect from light.
Medicines must not be used past the expiry date.
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